A high-throughput, high-resolution imager for multi-fluorescence imaging of 3D and 2D cultured cells.
Description
Research field
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Quantification and analysis for organoids, spheroids and general 2D cultured cells
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Cancer drug research and regenerative medicine
High-end model for both 2D and 3D culture analysis
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Possible to observe laminar cells such as epithelial cells clearly at the same level as phase-contrast microscope
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A high-throughput imager for a variety of applications such as single cell cloning, ES/iPS cell and organoids morphology analysis
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Function enhancement by plug-in software
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Automation systems (optional)
Multi-fluorescence imaging / High-throughput
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1 minute to scanning and 30 seconds analyzing
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Multi-fluorescence imaging and analysis available(Optional)
Features
1. Multi-fluorescence imaging and analysis
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Multi-fluorescence imaging and analysis
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Bright field and 3 fluorescent colors are automatically and continuously imaged with the simultaneous loading of LED fluorescent filter
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Line up of 5 types of fluorescent filters
2. Meniscus-less
Less meniscus and clear imaging even at the peripheral area
Bright field
Detect those areas
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Unique hyper-centric and tele-centric optical systems enables a high-resolution imaging of whole well including the marginal area of well
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Lens have 2 resolution which has 0.8um/pix and 4um/pix
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Equipped with high accurate extraction algorithm even cells soon after seeing
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High speed mode provide 60 sec/ 96 well plate and 70 sec/ 384 well plate.
3. Deep Learning Plug-in (optional)
image courtesy of Prof. Yun Chen,Far Eastern Memorial Hospital, TW
4. Neurite elongation plug-in (optional)
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Multi-object analysis, such as neurite elongation, is provided as a plug-in software
Cell body , Neurite
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Deep Learning to extract and quantify only grown organoids
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High confluence and non-uniform images can be accurately extracted and measured using Deep Learning
5. 3D cellular imaging
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Equipped with a proprietary lens with a deep depth of field suitable for 3D cultured cell imaging and illumination
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Z-stacking imaging and focus composition functions
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Compatible with F-bottom, V-bottom, U-bottom, various SBS formats and microwell plates as standard
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Functional specialty plates such as plates for 3D culture, Corning® Elplasia® (Corning Japan) and EZSPHERE (AGC Techno Glass Co., Ltd.) are also available
6. Automation system
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Automation by connecting external devices such as plate stacker and incubator with a plate transfer robot
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Automatically captures up to 200 images per day by robotization, streamlining a complicated workflow