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A high throughput, high-resolution imager

for label free profiling of 2D and 3D cell culture 

Description

Research field

  • Quantification and analysis for organoids, spheroids and general 2D cultured cells

  • Cancer drug research and regenerative medicine

 

High-end model for both 2D and 3D culture analysis

  • Possible to observe laminar cells such as epithelial cells    clearly at the same level as phase-contrast microscope

  • A high-throughput imager for a variety of applications such as single cell cloning, ES/iPS cell and  organoids morphology analysis

  • Function enhancement by plug-in software

  • Automation systems (optional)

Fluorescence imaging / High-throughput

  • ​1 minute to scanning and 30 seconds analyzing

  • Fluorescence imaging and analysis available (Optional)

Features

1. High Speed and Gentle

  • Capture whole well in whole plate with high speed scanning.

  • Nonstop continuous imaging by 4.2Megapixel sensor and unique optical system.

  • High speed mode provide 60 sec/ 96 well plate and 70 sec/ 384 well plate.

  • Non-moving micro well plates, prevent cell moving, media shaking.
    *1 High speed mode against 96well-plate.

Fluorescence imaging and analysis

2. High quality

  • Unique hyper-centric and tele-centric optical system enables a high-resolution imaging of whole well including area around the edge of well

  • Lens have 2 resolution which has 0.8um/pix and 4um/pix

  • ​Equipped with high accurate extraction algorithm even cells soon after seeing

  • Fluorescence imaging capability (optional) enables to get not only fluorescence image but also superimposed bright-field and fluorescence image

  • Available for Imaging tissue section on preparation 

​Less meniscus and clear imaging even at the peripheral area

​Imaging tissue sections by color

3. Excellent Accuracy

  • Cell3iMager duos learns complicated cell morphological characters and classify automatically cell

  • Enables growth test, drug efficiency test and more analysis in bright-field without some reagents

4. 3D cellular imaging

  • Equipped with a proprietary lens with a deep depth of field suitable for 3D cultured cell imaging and illumination

  • Z-stacking imaging and focus composition functions

  • Compatible with F-bottom, V-bottom, U-bottom, various SBS formats and microwell plates as standard

  • Functional specialty plates such as plates for 3D culture, Corning® Elplasia® (Corning Japan) and EZSPHERE (AGC Techno Glass Co., Ltd.) are also available

5. Function enhancement by plug-in software

  • Enable to add useful functions such as neurite elongation by plug-in software

6. Automation system

オートメーションシステム画像ENG duos.jpg
  • Automation by connecting external devices such as plate stacker and incubator with a plate transfer robot

  • Automatically captures up to 200 images per day by robotization, streamlining a complicated workflow

Specification

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